Glomerular filtration rate

Estimates the rate at which the kidneys filter plasma by dividing the urine concentration of a marker substance times the urine flow rate by its plasma concentration. It is used to assess kidney function.

\mathrm{GFR} = \frac{\mathrm{U}_{x} \times \dot{V}}{\mathrm{P}_{x}}

What the symbols mean

glomerular filtration rate, the volume of plasma cleared per unit time (mL/min)
urine concentration of the marker substance x (mg/mL or mmol/L)
urine flow rate, the volume of urine produced per unit time (mL/min)
plasma concentration of the marker substance x (mg/mL or mmol/L)

About this formula

  • FieldBiology and medicine
  • TopicRenal physiology
  • LevelUniversity
  • Also calledGFR formula, renal function test, creatinine clearance, kidney filtration rate, urine clearance formula, clearance formula
  • SourceWikidata Q1542839

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