Henderson–Hasselbalch equation

Estimates the pH of a buffer or weak acid solution from the acid dissociation constant and the ratio of conjugate base to acid concentrations. It is widely used for preparing buffers and for reasoning about acid-base equilibria in biological and chemical systems.

\mathrm{pH} = \mathrm{p}K_\mathrm{a} + \log\frac{[\mathrm{A}^-]}{[\mathrm{HA}]}

What the symbols mean

negative decimal logarithm of the hydrogen ion activity of the solution
negative decimal logarithm of the acid dissociation constant K_a of the weak acid
molar concentration of the conjugate base
molar concentration of the weak acid

About this formula

  • FieldChemistry
  • TopicAcid-base equilibria
  • LevelUniversity
  • Also calledHenderson-Hasselbalch equation, pH of buffer solution, buffer equation, pH of weak acid, pKa equation, pH pKa log ratio
  • SourceWikidata Q601818

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